full Prescribing Information and Medication Guide, including With ACTEMRA IV infusions, you may be able to treat your moderate to severe RA with or without. Full Prescribing Information ACTEMRA is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have. Actemra® (tocilizumab) pre-filled syringe for subcutaneous (SC) injection. Patients Consumer Medicine Information (CMI). Healthcare Professionals.
|Published (Last):||11 July 2011|
|PDF File Size:||18.31 Mb|
|ePub File Size:||4.7 Mb|
|Price:||Free* [*Free Regsitration Required]|
For more severe reactions such as hives, difficulty breathing, chest pain, high or low blood pressure, swelling of predcribing and hands, fever, chills or anaphylaxis or when mild reactions persist despite slowing the infusion, stop the infusion and treat the acute reaction.
Pre-Infusion Checklist Confirm the following: To learn more, call or talk to your healthcare provider to register.
Tier Description 1 This drug is available at knformation lowest co-pay. Dilute to mL in 0. Infections The rate of infections was Medication Guides Medication Guide: View explanations for tiers and restrictions. An infection, think you may have an infection, are being treated for an infection, or get a lot of infections that return. Serious allergic reactions, including death, can happen with ACTEMRA infusions or injections, even if they did not occur with an earlier infusion or injection.
Managing Infusion Reactions Acute infusion reaction prescribinh occur during the administration of tocilizumab or within 24 hours of infusion. Tell your healthcare provider if you have these or any other side effect that bothers you or does not go away:.
QL Quantity Limits Drugs that have quantity limits associated with each prescription. This drug is available at a middle level co-pay. Tocilizumab has not been studied in combination with biological DMARDs eg, TNF antagonists, IL-1R antagonists, anti-CD20 monoclonal antibodies, selective costimulation modulators and its use should be avoided in combination with these agents because of increased immunosuppression and risk of infection.
ACTEMRA® RA Treatment Information for Rheumatologists
Half-life in GCA patients: The most common ISRs were erythema, pruritus, pain, and swelling at the injection site. If you have polyarticular juvenile idiopathic informatoon PJIA you will have blood tests done every 4 to 8 weeks during treatment.
This restriction requires that specific clinical criteria be met prior to the approval of the prescription. The link you have selected will take you away from this site to one that is not owned or controlled by Genentech, Inc. The infusion should be administered over 60 minutes, and must be administered with an infusion set.
Administration IV Compatibility 0. This can make you more likely to get infections or make any current infection worse. In the open-label extension over an average duration of 73 weeks of treatment, the overall rate of infections was per patient-years.
Physicians are encouraged to register patients and pregnant women are encouraged to register themselves by calling Certolizumab Cimzia Medication Guide: Pegloticase Krystexxa Medication Guide: The limited available data with ACTEMRA in pregnant women are not sufficient to determine whether there is a drug-associated risk for major birth defects and miscarriage. ST Step Therapy Drugs that have step therapy associated with each prescription. For full Safety Informationplease see below. ACTEMRA is an immunosuppressant, and treatment with immunosuppressants may result in an increased risk of malignancies.
Formulary Formulary Patient Discounts. The above information is provided for general informational and educational purposes only. Dilute to 50 mL in 0. Impact of treatment with tocilizumab on demyelinating disorders is unknown, but multiple sclerosis and chronic inflammatory demyelinating polyneuropathy were reported rarely in RA clinical studies; monitor for signs and symptoms potentially indicative of demyelinating disorders.
Resume at mg every other week and increase frequency to every week as clinically appropriate. Tocilizumab should not be given to patients who have experienced anaphylaxis or other severe hypersensitivity and not re-challenged.
In the open-label extension over an average duration of 73 weeks of treatment, the overall rate of serious infections was Call Help Get more information. Obtain vital signs temperature, blood pressure and pulse upon arrival, after initiation of the infusion, upon discontinuing the infusion and before the patient departs the facility.
The recommended dosage given as IV infusion given once every 4 weeks is Patients less than 30 kg weight: Administer first SC dose instead of the next scheduled IV dose.
Click “OK” if you are a healthcare professional. Indicated for adults with moderate-to-severe active rheumatoid arthritis with inadequate response to 1 or more disease modifying antirheumatic drugs DMARDs as an IV infusion or SC injection.
inormation Most Popular Articles According to Rheumatologists. Most common side effects Tell your healthcare provider if you have these or any other side effect that bothers you or does not go away: Resume mg at every other week and increase frequency to every week as clinically appropriate. Patients less than 30 kg weight: Do you need help?
Dosage modifications may be required. You can find this form below. The solution should be protected from light. Tocilizumab Actemra Medication Guide: Non-Medicare Plans Medicare Plans.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
Increased blood pressure also called hypertension. Biosimilar Infliximab Inflectra Hotline: